Optimal control with MANF treatment of photoreceptor degeneration
نویسندگان
چکیده
منابع مشابه
rd1 Photoreceptor Degeneration: Photoreceptor Rescue and Role of Metalloproteases in Retinal Degeneration Ahuja Jensen, Poonam
Currently much attention is focused on glutathione S transferase (GST)-induced suppression of apoptosis. The objective of our studies was therefore to see if GST isoenzymes rescue photoreceptors in retinal explants from rd1/rd1 mice, in which photoreceptors degenerate rapidly. Eyes from C3H rd1/rd1 and / mice were collected at various time points between postnatal day (PN) 2 and PN28. Localizat...
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چکیده ندارد.
15 صفحه اولrd1 Photoreceptor Degeneration: Photoreceptor Rescue and Role of Metalloproteases in Retinal Degeneration
Currently much attention is focused on glutathione S transferase (GST)-induced suppression of apoptosis. The objective of our studies was therefore to see if GST isoenzymes rescue photoreceptors in retinal explants from rd1/rd1 mice, in which photoreceptors degenerate rapidly. Eyes from C3H rd1/rd1 and / mice were collected at various time points between postnatal day (PN) 2 and PN28. Localizat...
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PURPOSE The Wnt pathway is an essential signaling cascade that regulates multiple processes in developing and adult tissues, including differentiation, cellular survival, and stem cell proliferation. The authors recently demonstrated altered expression of Wnt pathway genes during photoreceptor death in rd1 mice, suggesting an involvement for Wnt signaling in the disease process. In this study, ...
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In this paper, we studied and formulated the relapsed SIR model of a constant size population with standard incidence rate. Also, the optimal control problem with treatment and vaccination as controls, subject to the model is formulated. The analysis carried out on the model, clearly showed that the infection free steady state is globally asymptotically stable if the bas...
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ژورنال
عنوان ژورنال: Mathematical Medicine and Biology: A Journal of the IMA
سال: 2019
ISSN: 1477-8599,1477-8602
DOI: 10.1093/imammb/dqz003